Not sure if this thread is still active but I wanted to post my experiences as they may help someone.
I have a PCV installed w/o Auto Tune (aka closed loop, not using O2 sensors). I'm using a canned map Fuel Moto loaded on the device when they sent it to me. My bike is a '12 FLTRX with Monster Rounds, a Fuel Moto headpipe (no cat), and FM intake, and stock everything else.
Last summer I went on a big trip which took my from my hometown of San Diego (sea level) to over a few 10,000' passes. I spent 3 days hiking in Yosemite and was riding around those 3 days at elevations between 7,000 and 10,000. Power seemed fine even up at 10k however you could hear a slight difference in the engine. I didn't have any trouble accelerating up hill fully loaded. Heat was fine (although at 10k it's usually colder anyways). The only thing I noticed was the pipe sound was just a little off and then when I got back down into lower elevations a little bit more exhaust coloration around my tail pipe (which I'm guessing is because the bike wasn't using the fule/air mixture as efficiently at those high altitudes).
I think the PCV without Auto Tune works more than fine when moving between altitudes.
However, since I am a perfectionist and love my bike running like a top in any condition I do plan to install the Auto Tune sometime this winter. Someone in this same situation will have to make the personal choice if the cost is worth it for them. Either way the PCV performs high up, you just might not be running as efficient.
2012 FLTRX - stage 1.5 headwork, dragos 580 cams, 10.25 comp, FM stage 1 intake, dragula 2, TTS, 13" windvest, 14" evil apes, JRI 12" shocks, progressive monotubes, hertz and alpine, hawg wired amp, custom LED gauges, custom dynamics LED signals, lots o' powder coat
San Diego, CA